Radiation-Associated Secondary Angiosarcoma of the Breast: Case Report and Literature Review
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Abstract
Radiation-Associated Angiosarcoma (RAAS) of the breast is a rare but highly aggressive malignancy that arises as a late complication of radiotherapy. Its incidence is increasing alongside the widespread use of breast-conserving treatment. The paper presents a case of a 57-year-old female with a history of bilateral breast cancer, treated with surgery and radiotherapy, who developed progressive cutaneous lesions of the right breast. Histopathological evaluation confirmed secondary angiosarcoma. Despite surgical management, early recurrence occurred, requiring systemic chemotherapy. This report highlights the aggressive clinical course of RAAS and underscores the importance of early diagnosis and multidisciplinary management.
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