Antipsychotics, Hypothermia, Undressing, and Death
Main Article Content
Abstract
One of the lesser-known adverse effects of antipsychotic medication is hypothermia, a significant and protracted plunge in body temperature. Known risk factors are older age and exposure to a new-for-the-person antipsychotic drug. Hypothermia impairs cognitive function, often resulting in a delirium that can paradoxically induce the prescription of escalating doses of the offending drug. As hypothermia increases, the subjective experience of the person may be one of overwhelming heat that can lead to the person shedding protective clothing, an action that can precipitate death.
Downloads
Article Details
Copyright (c) 2017 Seeman MV.

This work is licensed under a Creative Commons Attribution 4.0 International License.
Maytal G, Smith FA, Stern TA (2006) Naked patients in the General Hospital: Differential diagnosis and management strategies. Psychosomatics 47: 486-490. Link: https://goo.gl/BFkzkO
Simon RI (2008) Naked suicide. J Am Acad Psychiatry Law 36: 240-245. Link: https://goo.gl/Hp6HSA
Lester D (2015) Suicide as a staged performance. Compr Psychol 4: Article 18. Link: https://goo.gl/VKPv96
Seeman MV (2011) Sleepwalking, a possible side effect of antipsychotic medication. Psychiatr Quart 82: 59-67. Link: https://goo.gl/d7a2zE
Van Marum RJ, Wegewijs MA, Loonen AJM, Beers E (2007) Hypothermia following antipsychotic drug use. Eur J Clin Pharmacol 63: 627-631 Link: https://goo.gl/HZFEi9
Siddiqui JA, Qureshi SF, Al Zahrani (2016) Olanzapine-induced hypothermia: A rare case report. J Behav Health 5: 191-193. Link: https://goo.gl/0Jumcx
Dovjak M. Shukuya M, Krainer A (2014) Individualisation of personal space in hospital environment. Int J Exergy 14: 125-155. Link: https://goo.gl/Vc2ajo
Brown DJA, Brugger H, Boyd J, Paal P (2012) Accidental hypothermia. N Eng J Med 367: 1930-1938. Link: https://goo.gl/QtPPMB
Rothschild MA (2004) Lethal hypothermia – paradoxical undressing and hide-and-die syndrome can produce very obscure death scenes. In: Tsokos M, editor. Forensic Pathology Reviews 1: Totowa, NJ: Humana Press Inc 263-272. Link: https://goo.gl/kgKD23
Brändström H, Eriksson A, Giesbrecht G, Ängquist KA, Haney M (2012) Fatal hypothermia: an analysis from a sub-arctic region. Int J Circumpol Heal 71: 1-7. Link: https://goo.gl/MBlDDN
Docx KF, Simone A, Ramet J, Mertens L, Govaert P (2012) Olanzapine-associated hypothermia in an adolescent anorexic girl. Open J Clin Diag 2: 76-80. Link: https://goo.gl/OU4M1J
Kreuzer P, Landgrebe M, Wittmann M, Schecklmann M, Poeppl TB, et al. (2012) Hypothermia associated with antipsychotic drug use: a clinical case series and review of current literature. J Clin Pharmacol 52: 1090-1097. Link: https://goo.gl/RQjreH
Andreeva-Gateva PA, Gatev TN, Nachova R, Tafradjiiska-Hadjiolova RK, Grozeva M (2016) Hypothermia in a patient treated with antipsychotics. J Biomed Clin Res 9: 55-58. Link: https://goo.gl/327v3l
Honda T, Fujimoto K, Miyao Y (2016) Influence of weather conditions on the frequent onset of acute myocardial infarction. J Cardiol 67: 42-50. Link: https://goo.gl/5HzWA1
Nguyen JL, Link MS, Luttmann-Gibson H, Laden F, Schwartz J, et al. (2015) Drier air, lower temperatures, and triggering of paroxysmal atrial fibrillation. Epidemiology 26: 374-380. Link: https://goo.gl/O6FDRW
Asnis G (1977) Tardive dyskinesia: Is it or is it not? A review of the problems of diagnosis and case study. Dis Nerv Syst 38: 856-859. Link: https://goo.gl/6JwzTG