Gastrointestinal stromal tumor revealed by hemorrhagic shock

Main Article Content

Yassine Lemfadli*
Hala Aouroud
Abderrahmane Jallouli
Adil Ait Errami
Sofia Oubaha
Zouhour Samlani
Khadija Krati

Abstract

Gastrointestinal Stromal Tumors (GISTs) are rare tumors of the digestive tract. The small intestine is the second most frequent localization of GIST after the stomach. We report a case of the ileal stromal tumor. The patient was admitted with a picture of hemorrhagic shock due to massive rectal bleeding. The fiberscope performed after stabilization was not objectified at the origin of the document while the CT scan objectified a mass of tissue density at the level of the right iliac fossa. Given the increasing evolution with the recurrence of patients to a target of a laparotomy for diagnostic and therapeutic purposes objectifying the tumor of the right iliac fossa at the expense of the ileum. The surgical procedure consisted of a major segmental resection of the tumor with ileo-ileal anastomosis. The anatomopathological study confirmed the diagnosis of the stromal tumor with good evolution. Through a general review of the literature, we have described the various clinical, para-clinical, anatomopathological, prognostic, and current therapeutic aspects specific to these tumors.

Downloads

Download data is not yet available.

Article Details

Lemfadli, Y., Aouroud, H., Jallouli, A., Errami, A. A., Oubaha, S., Samlani, Z., & Krati, K. (2022). Gastrointestinal stromal tumor revealed by hemorrhagic shock. Global Journal of Medical and Clinical Case Reports, 9(1), 018–020. https://doi.org/10.17352/2455-5282.000149
Case Reports

Copyright (c) 2022 Lemfadli Y, et al.

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Coindre JM, Emile JF, Monges G, Ranchère-Vince D, Scoazec JY (2005) Gastrointestinal stromal tumors: definition, histological, immunohistochemical, and molecular features, and diagnostic strategy. Ann Pathol 25: 358-385. Link: https://bit.ly/3tG2QxT

Martí Obiol R, Garcés Albir M, López Mozos F, Ortega Serrano J (2013) Surgical treatment of gastrointestinal stromal tumours. Analysis of our experience. Cir Esp 91: 38-43. Link: https://bit.ly/3IUWXn6

Artigas Raventós V, López Pousa A, Ortega Medina L, de Liaño Argüelles AD, Fernández Hernández JA, et al. (2013) Primary, Non-metastatic Gastrointestinal Stromal Tumor Surgery: Results of the GRISK Study. Cir Esp 91: 96-102. Link: https://bit.ly/3HMue2x

Rubin BP, Singer S, Tsao C, Duensing A, Lux ML, et al. (2001) KIT activation is a ubiquitous feature of gastrointestinal stromal tumors. Cancer Res 61: 8118- 8121. Link: https://bit.ly/3CuHasD

Gupta P, Tewari M, Shukla HS (2008) Gastrointestinal Stromal Tumor. Surg Oncol 17: 129-138. Link: https://bit.ly/3sROefR

Balaton AJ, Coindre JM, Cvitkovic F (2001) Tumeurs stromales digestives. Gastroenterol Clin Biol 25: 473-482.

Miettinen M, Lasota J (2006) Gastrointestinal stromal tumors: review on morphology, molecular pathology, prognosis, and differential diagnosis. Arch Pathol Lab Med 130: 1466-1478. Link: https://bit.ly/3Kkszmq

Tateishi U, Hasegawa T, Satake M, Moriyama N (2003) Gastrointestinal stromal tumor.correlation of computed tomography findings with tumor grade and mortality. J Comput Assist Tomogr 27: 792-798. Link: https://bit.ly/3KnPf52

Serraj I, Amrani L, Atitar I, Kanouni N, Al Baroudi S, et al. (2008) Obscure gastrointestinal bleeding due to jejunal stromal tumor: the contribution of capsule endoscopy. Gastroenterol Clin Biol 32: 1022-1024.

Hueman MT, Schulick RD (2008) Management of gastrointestinal stromal tumors. Surg Clin North Am 88: 599–614. Link: https://bit.ly/3hUnSDH

Gleevec (imatinib mesylate) Prescribing information. Link: https://bit.ly/3i8pR7D

Eisenberg BL, Harris J, Blanke CD, Demetri GD, Heinrich MC, et al. (2009) Phase II trial of neoadjuvant/adjuvant imatinib mesylate (IM) for advanced primary and metastatic/recurrent operable gastrointestinal stromal tumor (GIST): early results of RTOG 0132/ACRIN 6665. J Surgical Oncology 99: 42–47. Link: https://bit.ly/3vRsRgG